Marine microorganisms as a source of bioactive agents

Microb Ecol. 1986 Mar;12(1):65-78. doi: 10.1007/BF02153223.


Several ecological factors of the marine environment were used in developing a strategy for discovering useful bioactive agents from marine microorganisms. By consideration of sea water requirements, production and degradation of marine polymers, and plasmid content, several novel anti-malarial antibiotics, anti-tumor polysaccharides, glucan-degrading enzymes, and aminoglycoside antibiotics were found.