We experimentally study the factors that limit the span in frequency combs derived from the crystalline whispering gallery mode resonators. We observe that cavity dispersion is the key property that governs the parameters of the combs resulting from cascaded four wave mixing process. Two different regimes of comb generation are observed depending on the precise cavity dispersion behavior at the pump wavelength. In addition, the comb generation efficiency is found to be affected by the crossing of modes of different families. The influence of Raman lasing and its dependence on temperature is discussed.