Effects of single aortic clamping versus partial aortic clamping techniques on post-operative stroke during coronary artery bypass surgery

Cardiovasc J Afr. 2013 Jul;24(6):213-7. doi: 10.5830/CVJA-2013-038.

Abstract

Background: The aim of this study was to compare the effects of single-clamping and partial-clamping techniques on postoperative stroke during coronary artery bypass surgery.

Methods: Between December 2008 and December 2012, 2 000 patients who underwent coronary artery bypass grafting in two hospitals were analysed. Post-operative neurological complications were analysed retrospectively in these patients. The cases were divided into two groups: in group 1, 1 500 patients were analysed, in whom proximal anastomosis was performed with partial clamping in a beating heart (n = 1 500, 846 male, 654 female; mean age 63.25 ± 5.72 years; range 43-78 years). In group 2, 500 patients were analysed, in whom proximal anastomosis had been performed by other surgical teams in another hospital, with cross clamping in a resting heart with cardioplegia (n = 500, 296 male, 214 female; mean age 64.83 ± 8.12 years; range 41-81 years). During 30 days post-operatively, neurological deficits, stroke incidence and the relationship of the clinical situation to mortality were analysed.

Results: For both groups, patients were similar in terms of patient characteristics. In group 2, cross-clamp duration and perfusion time were longer; however, time of hospital stay was similar in the two groups. Post-operative stroke was seen in 26 patients in group 1 (1.73%) and in nine in group 2 (1.8%). The difference between the two groups was not statistically significant (p = 0.92). All stroke patients were over the age of 55 years. Seven of the stroke patients died (21.1%). In total, 31 patients died because of multiple organ failure in the postoperative 30 days (group 1: 1.6%; group 2: 1.4%) (p = 0.91). Smoking, diabetes mellitus, hypertension, atrial fibrillation, peripheral vascular disease and hypercholesterolaemia were found to be factors that affected stroke development. Mean duration of hospital stay was 5.1 ± 2.8 days in group 1 and 4.9 ± 3.6 days in group 2 and the difference between the two groups was not statistically significant (p = 0.46).

Conclusion: In patients without plaques in the aorta, performing partial clamping did not increase stroke incidence.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aorta / pathology
  • Aorta / physiopathology
  • Aorta / surgery*
  • Constriction
  • Coronary Artery Bypass / adverse effects*
  • Coronary Artery Bypass / methods*
  • Coronary Artery Bypass / mortality
  • Female
  • Hemodynamics
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Operative Time
  • Perfusion
  • Plaque, Atherosclerotic
  • Retrospective Studies
  • Risk Factors
  • Stroke / diagnosis
  • Stroke / etiology*
  • Stroke / mortality
  • Stroke / therapy
  • Time Factors
  • Treatment Outcome