Acute kidney injury: Short-term statin therapy for prevention of contrast-induced AKI

Nat Rev Nephrol. 2014 Jan;10(1):8-9. doi: 10.1038/nrneph.2013.249. Epub 2013 Nov 12.


Two recent studies suggest that periprocedural statin administration can prevent contrast-induced acute kidney injury in cardiac patients undergoing percutaneous coronary intervention and in renal patients undergoing angiography, with or without intervention. These studies support the routine administration of potent statins before contrast media infusion in these vulnerable patients.

MeSH terms

  • Acute Kidney Injury / chemically induced
  • Acute Kidney Injury / prevention & control*
  • Contrast Media / adverse effects*
  • Coronary Angiography / adverse effects*
  • Coronary Angiography / methods
  • Drug Administration Schedule
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage*
  • Time Factors


  • Contrast Media
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors