Acute kidney injury: Short-term statin therapy for prevention of contrast-induced AKI

Dimitri P Mikhailidis; Vasilios G Athyros

doi:10.1038/nrneph.2013.249

Acute kidney injury: Short-term statin therapy for prevention of contrast-induced AKI

Nat Rev Nephrol. 2014 Jan;10(1):8-9. doi: 10.1038/nrneph.2013.249. Epub 2013 Nov 12.

Authors

Dimitri P Mikhailidis¹, Vasilios G Athyros²

Affiliations

¹ Department of Clinical Biochemistry (Vascular Prevention Clinic), Royal Free Hospital, Royal Free and University College School of Medicine, Pond Street, London NW3 2QG, UK.
² Atherosclerosis and Metabolic Syndrome Outpatient Units, Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, 15 Marmara Street, 55132 Thessaloniki, Greece.

PMID: 24217459
DOI: 10.1038/nrneph.2013.249

Abstract

Two recent studies suggest that periprocedural statin administration can prevent contrast-induced acute kidney injury in cardiac patients undergoing percutaneous coronary intervention and in renal patients undergoing angiography, with or without intervention. These studies support the routine administration of potent statins before contrast media infusion in these vulnerable patients.

MeSH terms

Acute Kidney Injury / chemically induced
Acute Kidney Injury / prevention & control*
Contrast Media / adverse effects*
Coronary Angiography / adverse effects*
Coronary Angiography / methods
Drug Administration Schedule
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage*
Time Factors

Substances

Contrast Media
Hydroxymethylglutaryl-CoA Reductase Inhibitors