The use of computer-guided flapless dental implant surgery (NobelGuide) and immediate function to support a fixed full-arch prosthesis in fresh-frozen homologous patients with bone grafts

J Craniofac Surg. 2013 Nov;24(6):e551-8. doi: 10.1097/SCS.0b013e31829ac8e2.


The behavior of fresh-frozen homologous bone (FFB) when used in combination with computer-guided implant surgery has not been investigated yet, and there is a lack of clinical evidence in the literature. The purpose of this retrospective study is to evaluate the implant survival and related fixed full-arch prostheses at the 1- to 5-year follow-up when performed with immediate function using a flapless surgical procedure and computer-aided technology (NobelGuide; Nobel Biocare AB, Goteborg, Sweden) in patients previously treated with FFB grafts. Furthermore, the related values of torque and complications observed were analyzed and discussed. Clinical charts of patients with edentulous arches treated with FFB grafts and NobelGuide system with at least 1 year follow-up were reviewed retrospectively.A total of 65 patients met the criteria of inclusion, receiving a total of 342 implants and 77 full-arch prostheses, with a mean follow-up of 32.87 months (range, 1-5 years). Survival of implants and prostheses was high, reaching 96.5% and 95%, respectively. Factors significantly related to failure of the implants were smoking, position of the implant as last distal abutment, and fracture of basal maxillary bone. Prostheses survival was influenced by bruxism, failure of multiple implants, and torque level of implant equal to 0 at implant insertion. All implants and prostheses failures occurred in the first year. A higher torque level at implant insertion did not correspond to a lower risk of implant failure.Within the limitations of our retrospective study, this treatment modality was predictable with high survival rates and high insertion torque. However, a few implant and prosthetic failures were found, together with several complications.

MeSH terms

  • Adult
  • Aged
  • Allografts / transplantation*
  • Alveolar Ridge Augmentation / methods
  • Bone Transplantation / methods*
  • Bruxism / complications
  • Cohort Studies
  • Dental Implants* / adverse effects
  • Dental Prosthesis, Implant-Supported*
  • Dental Restoration Failure
  • Female
  • Follow-Up Studies
  • Humans
  • Immediate Dental Implant Loading*
  • Jaw, Edentulous / surgery*
  • Male
  • Maxillary Fractures / etiology
  • Middle Aged
  • Retrospective Studies
  • Smoking
  • Surgery, Computer-Assisted / methods*
  • Survival Analysis
  • Torque


  • Dental Implants