Nodal combined blue nevus and benign nevus cells in multiple axillary sentinel nodes in a patient with breast carcinoma: report of a case

Int J Surg Pathol. 2014 Sep;22(6):570-3. doi: 10.1177/1066896913509008. Epub 2013 Nov 12.

Abstract

Combined blue nevus and benign nevus cells were identified in the same sentinel lymph node. Blue nevus alone was also present in an additional sentinel lymph node in the same axilla in a patient who underwent needle localization, wide local excision, and sentinel lymph node biopsy for her pT1cN1mi(sn)M(na) invasive duct carcinoma of the breast. Of the 4 sentinel lymph nodes, 1 showed micrometastasis and 2 other lymph nodes showed blue nevus involving the capsule and trabeculae of the nodes. The patient had no significant previous clinical history of any skin tumors and had a negative clinical examination for malignant melanoma or pigmented skin lesions after the diagnosis of nodal blue nevus. To our knowledge, this is the first case report of combined blue nevi involving multiple sentinel lymph nodes in the same axilla. An equally interesting finding is the presence of benign nonpigmented nevus cells in continuation with the blue nevus in the same node.

Keywords: benign nevus cells; breast cancer; nodal combined blue nevus; sentinel node.

Publication types

  • Case Reports

MeSH terms

  • Axilla / pathology
  • Breast Neoplasms / pathology*
  • Carcinoma, Ductal, Breast / pathology*
  • Female
  • Humans
  • Lymphatic Metastasis / pathology*
  • Nevus, Blue / pathology*
  • Sentinel Lymph Node Biopsy