DoMosaics: software for domain arrangement visualization and domain-centric analysis of proteins

Bioinformatics. 2014 Jan 15;30(2):282-3. doi: 10.1093/bioinformatics/btt640. Epub 2013 Nov 12.


DoMosaics is an application that unifies protein domain annotation, domain arrangement analysis and visualization in a single tool. It simplifies the analysis of protein families by consolidating disjunct procedures based on often inconvenient command-line applications and complex analysis tools. It provides a simple user interface with access to domain annotation services such as InterProScan or a local HMMER installation, and can be used to compare, analyze and visualize the evolution of domain architectures.

Availability and implementation: DoMosaics is licensed under theApache License, Version 2.0, and binaries can be freely obtained from

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acyl-tRNA Synthetases / chemistry*
  • Amino Acyl-tRNA Synthetases / classification
  • Amino Acyl-tRNA Synthetases / genetics
  • Animals
  • Computer Graphics*
  • Drosophila melanogaster / enzymology
  • Drosophila melanogaster / genetics
  • Molecular Sequence Annotation
  • Phylogeny
  • Protein Interaction Domains and Motifs*
  • Proteins / chemistry*
  • Proteins / classification
  • Proteins / genetics
  • Software*


  • Proteins
  • Amino Acyl-tRNA Synthetases