Plasmonic nanoprobes for real-time optical monitoring of nitric oxide inside living cells

Pilar Rivera Gil; Carmen Vazquez-Vazquez; Vincenzo Giannini; M Pilar Callao; Wolfgang J Parak; Miguel A Correa-Duarte; Ramon A Alvarez-Puebla

doi:10.1002/anie.201306390

Plasmonic nanoprobes for real-time optical monitoring of nitric oxide inside living cells

Angew Chem Int Ed Engl. 2013 Dec 16;52(51):13694-8. doi: 10.1002/anie.201306390. Epub 2013 Nov 12.

Authors

Pilar Rivera Gil¹, Carmen Vazquez-Vazquez, Vincenzo Giannini, M Pilar Callao, Wolfgang J Parak, Miguel A Correa-Duarte, Ramon A Alvarez-Puebla

Affiliation

¹ Department of Physics, Philipps Universität Marburg, 35037 Marburg (Germany).

PMID: 24222643
DOI: 10.1002/anie.201306390

Abstract

An optical sensor was developed for the quantitative determination of intracellular nitric oxide. The sensor consists of plasmonic nanoprobes that have a coating of mesoporous silica and an inner gold island film functionalized with a chemoreceptor for NO.

Keywords: analytical methods; intracellular monitoring; nanostructures; nitrogen oxides; optical sensors.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biosensing Techniques / methods*
Nanostructures / therapeutic use*
Nitrogen Oxides / chemistry*

Substances

Nitrogen Oxides