Presacral ganglioneuroma with abnormal FDG uptake: a case report

Acta Chir Belg. 2013 Jul-Aug;113(4):298-300. doi: 10.1080/00015458.2013.11680932.


Ganglioneuromas are rare, benign, well-differentiated, slowgrowing tumors of the sympathetic nervous system, composed of large, mature neurons in a stroma composed of Schwann cells. Ganglioneuromas are derived from the neural crest cells and can arise anywhere from the base of the skull to the pelvis. The pre-sacral area is a very rare location for ganglioneuromas to develop. We describe the case of a 31 year old woman, who was incidentally found to have an abnormal pre-sacral mass. The following work-up, revealed the mass to be growing on imagery (computed tomography and magnetic resonance imagery) and fluorine-18 fluorodeoxiglucose avid. The mass was removed by assisted laparoscopy and was found to be a benign ganglioneuroma. This is the first described case of fluorine-18 fluorodeoxiglucose avid, pre-sacral, benign ganglioneuroma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Female
  • Fluorodeoxyglucose F18* / pharmacokinetics
  • Ganglioneuroma / diagnosis*
  • Ganglioneuroma / metabolism
  • Humans
  • Laparoscopy
  • Lumbosacral Plexus
  • Magnetic Resonance Imaging / methods*
  • Neoplasm Staging
  • Peripheral Nervous System Neoplasms / diagnosis*
  • Peripheral Nervous System Neoplasms / metabolism
  • Positron-Emission Tomography / methods*
  • Radiopharmaceuticals / pharmacokinetics


  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18