Brain Death Determination

J Intensive Care Med. 2015 Sep;30(6):326-37. doi: 10.1177/0885066613511053. Epub 2013 Nov 12.

Abstract

In the United States, each year 1% to 2% of deaths are brain deaths. Considerable variation in the practice of determining brain death still remains, despite the publication of practice parameters in 1995 and an evidence-based guideline update in 2010. This review is intended to give bedside clinicians an overview of definition, the causes and pitfalls of misdiagnosing brain death, and a focus on the specifics of the brain death determination process.

Keywords: absent brain stem reflexes; apnea test; brain death; irreversible brain injury.

Publication types

  • Review

MeSH terms

  • Brain Death / diagnosis*
  • Brain Death / diagnostic imaging
  • Cerebral Angiography
  • Diagnostic Errors
  • Electroencephalography
  • Humans
  • Practice Guidelines as Topic
  • Radionuclide Imaging
  • United States