Age-related changes of hyoid bone position in healthy older adults with aspiration

Laryngoscope. 2014 Jun;124(6):E231-6. doi: 10.1002/lary.24453. Epub 2013 Nov 13.

Abstract

Objectives/hypothesis: Aspiration, the passage of a bolus below the vocal folds, increases morbidity and mortality in the elderly by increasing the risk of aspiration pneumonia and other conditions. We hypothesized that altered position of the hyoid bone associated with aging may negatively affect airway protection during swallowing (i.e., aspiration) in older adults.

Study design: Retrospective study.

Methods: We re-reviewed computed tomography (CT) scans of the head from 40 older adults (65-80 years old), comprised of 20 aspirators and 20 nonaspirators, obtained from a previous cohort study. In addition, CT scans of the head from 40 young adults (20-40 years old) were retrieved from a medical records database. Three-dimensional reconstruction and 2-dimensional sagittal views were used to measure the distance between the mandible and hyoid bone. Comparisons between age groups, genders, and aspiration status were made.

Results: Older adults had a larger distance between the hyoid and mandible in both latitude and longitudinal positions compared to the young adults. Among older males, there was evidence that the hyoid bone in the aspirators tended to be positioned more posterior compared to the nonaspirators.

Conclusions: The distance between the hyoid and mandible is increased with aging, and a more posterior position of the hyoid bone is correlated with aspiration in older males. These findings suggest that age-related changes in hyoid bone position may be a component of decreased swallowing safety and aspiration in older adults and warrant further investigation.

Level of evidence: N/A.

Keywords: Mandible; aging; aspiration; computed tomography; hyoid; swallowing.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Aging / physiology*
  • Cohort Studies
  • Deglutition / physiology
  • Deglutition Disorders / complications
  • Deglutition Disorders / diagnostic imaging*
  • Deglutition Disorders / physiopathology*
  • Female
  • Humans
  • Hyoid Bone / anatomy & histology*
  • Hyoid Bone / diagnostic imaging*
  • Imaging, Three-Dimensional*
  • Linear Models
  • Male
  • Mandible / anatomy & histology
  • Mandible / diagnostic imaging
  • Multivariate Analysis
  • Observer Variation
  • Reference Values
  • Reproducibility of Results
  • Respiratory Aspiration / etiology*
  • Respiratory Aspiration / prevention & control
  • Retrospective Studies
  • Risk Assessment
  • Sex Factors
  • Tomography, X-Ray Computed / methods
  • Young Adult