Early Predictors of Neurodevelopmental Outcome of Very Low-Birthweight Infants at Three Years

Dev Med Child Neurol. 1986 Apr;28(2):171-9. doi: 10.1111/j.1469-8749.1986.tb03851.x.


Seventy-nine premature infants weighting less than 1501 g at birth but appropriate for gestational age underwent a neurodevelopmental examination at one, three, six, nine and 12 months post-term, and a standard neurological examination and the Stanford-Binet Intelligence Scale at three to four years of age. Children were classified as normal, suspect or abnormal on the three-year neurological examination, on the IQ test, and on composite neurodevelopmental outcome at age three years. Results showed that items from both the nine- and 12-month neurodevelopmental examinations correctly classified about 80 per cent of the children as to composite outcome at three years. In addition, the 12-month examination enabled correct prediction for 89 per cent of the children as to neurological outcome and for 82 per cent as to IQ. Neurodevelopmental examination of high-risk infants in the last quarter of the first year of life (post-term) should assist pediatricians in predicting which children will be normal and which will require early intervention.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebral Palsy / diagnosis
  • Child, Preschool
  • Developmental Disabilities / diagnosis*
  • Female
  • Humans
  • Infant, Low Birth Weight / psychology*
  • Infant, Newborn
  • Infant, Premature / psychology*
  • Intelligence
  • Male
  • Motor Skills
  • Neuropsychological Tests*
  • Stanford-Binet Test