Abstract
A recombinant clone which covers the human salivary alpha-amylase gene in a single insert has been isolated from a human genomic DNA library using a human salivary alpha-amylase cDNA as a probe. Restriction mapping and nucleotide (nt) sequence analysis revealed that this gene is approx. 10 kb long and is separated into eleven exons by ten introns. Its 5'-flanking region has some sequence homology with that of mouse salivary alpha-amylase gene [Schibler et al., J. Mol. Biol. 155 (1982) 247-266].
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Cloning, Molecular
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DNA / analysis
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DNA Restriction Enzymes
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Genes*
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Humans
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Liver / enzymology
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Mice
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Microscopy, Electron
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Molecular Weight
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Pancreas / enzymology
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Poly A / genetics
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RNA / genetics
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RNA, Messenger
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Saliva / enzymology*
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Transcription, Genetic
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alpha-Amylases / genetics*
Substances
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RNA, Messenger
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Poly A
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RNA
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DNA
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DNA Restriction Enzymes
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alpha-Amylases
Associated data
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GENBANK/K02213
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GENBANK/K02214
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GENBANK/M18714
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GENBANK/M18715
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GENBANK/M18716
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GENBANK/M18717
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GENBANK/M18718
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GENBANK/M18719
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GENBANK/M18720
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GENBANK/M18721
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GENBANK/M18722
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GENBANK/M18723
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GENBANK/M18724
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GENBANK/M18725
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GENBANK/M18726
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GENBANK/M18727
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GENBANK/M18781
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GENBANK/M18782
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GENBANK/M18783
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GENBANK/M18784
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GENBANK/M18785
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GENBANK/M18786