Seizure as an initial presentation of human immunodeficiency virus: acute toxoplasmosis mimicking glioblastoma multiforme

BMJ Case Rep. 2013 Nov 14;2013:bcr2013200795. doi: 10.1136/bcr-2013-200795.


We present a case of a 46-year-old man with a history significant only for hypertension and depression that presented with a new onset seizure resulting from a right parietal lobe mass. Further evaluation determined the parietal mass to be central nervous system toxoplasmosis, which was the initial presentation of his underlying HIV/AIDS. This case provided a diagnostic challenge and demonstrates the importance of a thorough evaluation as it pertains to a newly diagnosed brain lesion.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / diagnosis*
  • Diagnosis, Differential
  • Glioblastoma / diagnosis*
  • HIV Infections / complications*
  • HIV Infections / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neuroimaging
  • Parietal Lobe / pathology
  • Seizures / etiology*
  • Toxoplasmosis, Cerebral / complications*
  • Toxoplasmosis, Cerebral / diagnosis
  • Toxoplasmosis, Cerebral / etiology
  • Toxoplasmosis, Cerebral / pathology