Acquired aplastic anemia in children

Pediatr Clin North Am. 2013 Dec;60(6):1311-36. doi: 10.1016/j.pcl.2013.08.011. Epub 2013 Oct 16.


This article provides a practice-based and concise review of the etiology, diagnosis, and management of acquired aplastic anemia in children. Bone marrow transplantation, immunosuppressive therapy, and supportive care are discussed in detail. The aim is to provide the clinician with a better understanding of the disease and to offer guidelines for the management of children with this uncommon yet serious disorder.

Keywords: Acquired aplastic anemia; Bone marrow failure; Bone marrow transplant for severe aplastic anemia in children; Immune-mediated aplastic anemia; Immunosuppressive therapy for severe aplastic anemia in children.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anemia, Aplastic / diagnosis
  • Anemia, Aplastic / etiology*
  • Anemia, Aplastic / therapy
  • Bone Marrow Transplantation
  • Child
  • Humans
  • Immunosuppressive Agents
  • Survival Rate
  • Treatment Outcome


  • Immunosuppressive Agents