A sting in the tale of TH2 immunity

Immunity. 2013 Nov 14;39(5):803-5. doi: 10.1016/j.immuni.2013.10.015.

Abstract

Allergies are widely considered misguided Th2 cell responses. In this issue, Palm et al. (2013) and Marichal et al. (2013) show that mice mount anti-venom Th2 cell responses that share components of the "allergic" response but confer protection.

Publication types

  • Comment

MeSH terms

  • Animals
  • Bee Venoms / enzymology*
  • Bee Venoms / toxicity*
  • Female
  • Hypersensitivity / immunology*
  • Immunity, Innate / immunology*
  • Immunoglobulin E / biosynthesis*
  • Immunoglobulin E / immunology*
  • Insect Proteins / immunology*
  • Interleukin-1 Receptor-Like 1 Protein
  • Lysophospholipids / immunology*
  • Phospholipases A2 / immunology*
  • Receptors, Interleukin / immunology*
  • Th2 Cells / immunology*

Substances

  • Bee Venoms
  • Il1rl1 protein, mouse
  • Insect Proteins
  • Interleukin-1 Receptor-Like 1 Protein
  • Lysophospholipids
  • Receptors, Interleukin
  • Immunoglobulin E
  • Phospholipases A2