Respiratory outcomes for the tiniest or most immature infants

Semin Fetal Neonatal Med. 2014 Apr;19(2):105-11. doi: 10.1016/j.siny.2013.10.006. Epub 2013 Nov 14.


Extremely low birth weight (<1000 g birth weight) or extremely preterm (<28 weeks of gestation) infants are surviving in greater numbers as neonatal care advances. Many of these survivors, especially those who develop bronchopulmonary dysplasia, have more respiratory ill health in the first years after discharge home, reduced respiratory function and impaired exercise capacity throughout childhood and into adulthood compared with term-born controls. It is important to establish the long-term respiratory outcomes for the tiniest or most immature survivors as they grow older, since they may contribute disproportionately to rates of chronic obstructive pulmonary disease and respiratory ill-health in adulthood.

Keywords: Bronchopulmonary dysplasia; Extremely low birth weight; Extremely premature; Infant; Respiratory function tests.

Publication types

  • Review

MeSH terms

  • Bronchopulmonary Dysplasia / physiopathology*
  • Humans
  • Infant
  • Infant, Extremely Low Birth Weight*
  • Infant, Extremely Premature*
  • Infant, Newborn