Supercluster takes a walk on the wild side

Trends Microbiol. 2013 Dec;21(12):617-8. doi: 10.1016/j.tim.2013.11.002. Epub 2013 Nov 14.

Abstract

In a recent Proc. Natl. Acad. Sci. USA paper by Wiemann et al., a gene supercluster for secondary metabolite production in Aspergillus fumigatus is genetically dissected. The analysis demonstrates that gene regulation takes place at different layers and that genes belonging to specific clusters are intertwined.

Publication types

  • Comment

MeSH terms

  • Aspergillus fumigatus / metabolism*
  • Cyclohexanes / metabolism*
  • Fatty Acids, Unsaturated / metabolism*
  • Genes, Fungal / physiology*
  • Indenes / metabolism*
  • Multigene Family / physiology*
  • Pyrrolidinones / metabolism*

Substances

  • Cyclohexanes
  • Fatty Acids, Unsaturated
  • Indenes
  • Pyrrolidinones