[Morphological changes in the cerebral cortex after a stroke]

Arkh Patol. 1986;48(4):44-51.
[Article in Russian]

Abstract

29 brains of right-handed persons who died within the period of 4 hours to 6 years after the stroke were studies. The patients had various disorders of speech and movements, partial or complete speech recovery was observed in 10 cases. Aphasias resulted from the lesions of associative fibers connecting the speech zones of the brain cortex, direct destruction of speech regions, in cases of hematoma pressure on cortex speech areas. Changes in neurons, nerve fibres and neuroglia in the cortex of speech areas were determined by the time passed after the stroke. They were also dependent on the site and size of the focus and, to a certain extent, correlated with a clinical picture. The changes also depended on localization and the size of lesion. Sometimes the changes correlated with clinical data. Clinical and morphological comparisons indicate that a correlation exists between speech recovery degree and the intensity of repairing processes in neurons and nerve fibres in cortical speech areas.

Publication types

  • English Abstract

MeSH terms

  • Acute Disease
  • Aged
  • Aphasia / pathology
  • Brain Ischemia / pathology
  • Cerebral Cortex / pathology*
  • Cerebral Hemorrhage / pathology
  • Cerebrovascular Disorders / pathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Speech Disorders / pathology
  • Time Factors