Retrotransposon silencing during embryogenesis: dicer cuts in LINE

PLoS Genet. 2013 Nov;9(11):e1003944. doi: 10.1371/journal.pgen.1003944. Epub 2013 Nov 7.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Argonaute Proteins / genetics*
  • DEAD-box RNA Helicases / genetics*
  • Embryonic Stem Cells / metabolism*
  • Long Interspersed Nucleotide Elements / genetics*
  • RNA Interference*
  • Ribonuclease III / genetics*

Substances

  • Ago2 protein, mouse
  • Argonaute Proteins
  • Dicer1 protein, mouse
  • Ribonuclease III
  • DEAD-box RNA Helicases

Grant support

The author is supported by an Australian NHMRC Career Development Fellowship (GNT1045237), NHMRC Project Grants GNT1042449, GNT1045991, and GNT1052303, and the European Union's Seventh Framework Programme (FP7/2007–2013) under grant agreement No. 259743 underpinning the MODHEP consortium. The funders had no role in the preparation of the manuscript.