Adherence to international follow-up guidelines in type 2 diabetes: a longitudinal cohort study in Luxembourg

PLoS One. 2013 Nov 11;8(11):e80162. doi: 10.1371/journal.pone.0080162. eCollection 2013.

Abstract

Introduction: Type 2 diabetes is associated with severe micro- and macro-vascular complications. Physicians' and patients' adherence to follow-up guidelines permits postponing or reducing these complications. The objectives were to assess the level of adherence to fundamental follow-up guidelines and determine patients' characteristics associated with this level of adherence in the context of Luxembourg, where no guidelines were implemented.

Study population: The exhaustive residing population treated for type 2 diabetes in Luxembourg during the 2000-2006 period (N = 21,068).

Methods: Seven fundamental criteria were extracted from international guidelines (consultation with the treating physician, HbA1c tests, electrocardiogram, retinal, dental, lipid and renal check-ups). The factors associated with the level of adherence to those criteria were identified using a partial proportional odds model.

Results: In 2006, despite 90% of the patients consulted at least 4 times their treating physician, only 0.6% completed all criteria; 55.0% had no HbA1c test (-8.6 points since 2000) and 31.1% had a renal check-up (+21.6 points). The sex (OR(male): 0.87 [95%CI, 0.83-0.92]), the nationality (OR(NonEU): 0.64 [0.52-0.78]), the type of antidiabetic treatment (ORoral: 1.48 [1.35-1.63], OR(mixed): 1.35 [1.20-1.52]) and the type of treating physician (ORG-ID: 0.47 [0.42-0.53]) were the main factors associated with the level of adherence in 2006 (3 or more criteria).

Conclusion: A large percentage of patients were not provided with a systematic annual follow-up between 2000 and 2006. This study highlighted the necessity to promote guidelines in Luxembourg, education for physicians and to launch a national discussion on a disease management program for diabetic patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / drug therapy
  • Diabetes Mellitus, Type 2 / physiopathology
  • Diabetes Mellitus, Type 2 / psychology*
  • Electrocardiography
  • Female
  • Follow-Up Studies
  • Glycated Hemoglobin / metabolism
  • Guideline Adherence / statistics & numerical data*
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Kidney Function Tests
  • Lipoproteins / blood
  • Luxembourg
  • Male
  • Middle Aged
  • Patient Compliance / psychology
  • Patient Compliance / statistics & numerical data*
  • Practice Guidelines as Topic
  • Proportional Hazards Models

Substances

  • Glycated Hemoglobin A
  • Hypoglycemic Agents
  • Lipoproteins
  • hemoglobin A1c protein, human

Grants and funding

Laurence M. Renard received a grant from the National Fund for Research, Luxembourg (EXT-BFR07-146). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.