Abstract
Angiotensin converting enzyme inhibitors have been used in the neonatal population for both cardiac and renal diseases. Past reports have described deleterious renal and neurological consequences as a result of these drugs. This report describes two infants receiving enalapril for different indications who suffered renal impairments, likely a result of concomitant diuretic use. These cases demonstrate the risks associated with ACE inhibitor use and the importance of vigilant monitoring when using these medications.
Keywords:
ACE inhibitors; Hypotension; congestive heart failure; oliguria.
MeSH terms
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Acute Kidney Injury / chemically induced*
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Anal Canal / abnormalities
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Anal Canal / surgery
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Angiotensin-Converting Enzyme Inhibitors / adverse effects*
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Enalapril / adverse effects*
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Esophagus / abnormalities
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Esophagus / surgery
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Heart Defects, Congenital / surgery
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Heart Septal Defects, Atrial / surgery
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Humans
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Infant
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Kidney / abnormalities
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Kidney / surgery
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Limb Deformities, Congenital / surgery
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Male
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Spine / abnormalities
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Spine / surgery
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Trachea / abnormalities
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Trachea / surgery
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Transposition of Great Vessels / surgery
Substances
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Angiotensin-Converting Enzyme Inhibitors
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Enalapril