"Set it and forget it": women's perceptions and opinions of long-acting topical vaginal gels

AIDS Behav. 2014 May;18(5):862-70. doi: 10.1007/s10461-013-0652-4.


Women's initial understandings and anticipated acceptability of long-acting vaginal gels as potential anti-HIV microbicides was investigated by exploring the perceptibility variables associated with prototype formulations. Four focus groups with 29 women, aged 18-45, were conducted to consider gel prototypes with varied physicochemical and rheological properties. Participants responded favorably to the concept of long-acting vaginal gels as microbicides. Distinctions in understandings and stated needs regarding product dosing, characteristics, and effectiveness offer valuable insights into product design. Long-acting vaginal gels capable of protecting against HIV/STIs will be a viable option among potential users, with dosing frequency being an important factor in willingness to use.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Administration, Intravaginal
  • Adolescent
  • Adult
  • Anti-Infective Agents, Local / administration & dosage*
  • Female
  • Focus Groups
  • HIV Infections / prevention & control*
  • Humans
  • Interviews as Topic
  • Patient Acceptance of Health Care / psychology*
  • Perception
  • Qualitative Research
  • Sexually Transmitted Diseases / prevention & control*
  • Time Factors
  • Vaginal Creams, Foams, and Jellies / administration & dosage*


  • Anti-Infective Agents, Local
  • Vaginal Creams, Foams, and Jellies