Abstract
Freeze-fracture methods were used to study intramembranous particles, which are believed to represent ectopic sodium channels in the paranodal axolemma, and their possible association with differences in action potential electrogenesis of maturing rat dorsal and ventral root fibers. Our results indicate that there is no significant association between paranodal axon membrane structure and the functional difference of dorsal and ventral root axons.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Action Potentials
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Animals
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Cell Membrane / ultrastructure
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Freeze Fracturing
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Ion Channels / physiology
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Ion Channels / ultrastructure*
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Motor Neurons / ultrastructure
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Neurons, Afferent / ultrastructure
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Rats
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Sodium / metabolism*
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Spinal Nerve Roots / physiology
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Spinal Nerve Roots / ultrastructure*