Platelet-derived PF4 reduces neutrophil apoptosis following arterial occlusion

Thromb Haemost. 2014 Mar 3;111(3):562-4. doi: 10.1160/TH13-08-0699. Epub 2013 Nov 21.

Authors

H Hartwig, M Drechsler, D Lievens, B Kramp, P von Hundelshausen, E Lutgens, C Weber, Y Döring, O Soehnlein¹

Affiliation

¹ Oliver Soehnlein, Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Pettenkoferstr. 9, 80336 Munich, Germany, Tel. : +49 89 5160 4365, E-mail oliver.soehnlein@gmail.com.

PMID: 24258616
DOI: 10.1160/TH13-08-0699

No abstract available

Publication types

Letter

MeSH terms

Animals
Antibodies, Blocking / pharmacology
Apoptosis / drug effects
Apoptosis / immunology
Arterial Occlusive Diseases / blood
Arterial Occlusive Diseases / immunology*
Blood Platelets / metabolism*
Cell Degranulation
Cell Separation
Cells, Cultured
Culture Media, Conditioned / metabolism*
Culture Media, Conditioned / pharmacology
Femoral Artery / surgery
Flow Cytometry
Humans
Inflammation / blood
Ischemia / blood
Ischemia / immunology*
Mice
Models, Animal
Neutrophils / drug effects*
Neutrophils / physiology
Platelet Activation / immunology
Platelet Factor 4 / metabolism*
Platelet Factor 4 / pharmacology
Secretory Vesicles / metabolism*

Substances

Antibodies, Blocking
Culture Media, Conditioned
Platelet Factor 4