The National Institutes of Health's Biomedical Translational Research Information System (BTRIS): design, contents, functionality and experience to date

J Biomed Inform. 2014 Dec;52:11-27. doi: 10.1016/j.jbi.2013.11.004. Epub 2013 Nov 19.

Abstract

The US National Institutes of Health (NIH) has developed the Biomedical Translational Research Information System (BTRIS) to support researchers' access to translational and clinical data. BTRIS includes a data repository, a set of programs for loading data from NIH electronic health records and research data management systems, an ontology for coding the disparate data with a single terminology, and a set of user interface tools that provide access to identified data from individual research studies and data across all studies from which individually identifiable data have been removed. This paper reports on unique design elements of the system, progress to date and user experience after five years of development and operation.

Keywords: Clinical research; Ontology; Research data repository; Research data warehouse; Translational research.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Biological Ontologies*
  • Biomedical Research / methods*
  • Database Management Systems*
  • Electronic Health Records
  • Humans
  • National Institutes of Health (U.S.)
  • Translational Medical Research / methods*
  • United States