Ongoing challenges in pharmacovigilance

Drug Saf. 2014 Jan;37(1):1-8. doi: 10.1007/s40264-013-0123-x.


While pharmacovigilance systems have made substantial progress in the past several decades, all pharmacovigilance systems face a common set of ongoing challenges in drug safety surveillance in five principal interrelated areas: engaging the public, collaboration and partnerships, incorporating informatics, adopting a global approach, and assessing the impact of efforts. In broad terms, these challenges are not new. Rather, advances in science and technology, along with more demanding societal expectations, have changed the nature of these challenges and provided new opportunities to move the field forward. Differences in organization and levels of development, as well as regional differences, necessarily imply that a single approach is not suitable for all regions, though sharing of best practices can help each region.

MeSH terms

  • Adverse Drug Reaction Reporting Systems / organization & administration*
  • Adverse Drug Reaction Reporting Systems / trends
  • Cooperative Behavior
  • Drug-Related Side Effects and Adverse Reactions / epidemiology*
  • Humans
  • Informatics
  • Pharmacovigilance*