Myocarditis after trimethoprim/sulfamethoxazole treatment for ehrlichiosis

Emerg Infect Dis. 2013 Dec;19(12):1975-7. doi: 10.3201/eid1912.121459.


The manifestations of human monocytic ehrlichiosis range from a mild febrile syndrome to a severe multisystem illness. Myocardial involvement is uncommon. We report a woman, 78 years of age, who was treated with trimethoprim/sulfamethoxazole after a tick bite, in whom myocarditis was subsequently diagnosed. She recovered completely after doxycycline therapy.

Keywords: Ehrlichia; bacteria; ehrlichiosis; myocarditis; tickborne; ticks; trimethoprim/sulfamethoxazole; zoonoses.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Ehrlichia chaffeensis / classification
  • Ehrlichiosis / complications*
  • Ehrlichiosis / diagnosis
  • Ehrlichiosis / drug therapy
  • Female
  • Humans
  • Myocarditis / diagnosis
  • Myocarditis / etiology*
  • Serotyping
  • Trimethoprim, Sulfamethoxazole Drug Combination / adverse effects
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use


  • Trimethoprim, Sulfamethoxazole Drug Combination