Recommendations for breast cancer surveillance for female survivors of childhood, adolescent, and young adult cancer given chest radiation: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group

Lancet Oncol. 2013 Dec;14(13):e621-9. doi: 10.1016/S1470-2045(13)70303-6.


Female survivors of childhood, adolescent, and young adult (CAYA) cancer who were given radiation to fields that include breast tissue (ie, chest radiation) have an increased risk of breast cancer. Clinical practice guidelines are essential to ensure that these individuals receive optimum care and to reduce the detrimental consequences of cancer treatment; however, surveillance recommendations vary among the existing long-term follow-up guidelines. We applied evidence-based methods to develop international, harmonised recommendations for breast cancer surveillance among female survivors of CAYA cancer who were given chest radiation before age 30 years. The recommendations were formulated by an international, multidisciplinary panel and are graded according to the strength of the underlying evidence.

Publication types

  • Practice Guideline
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Age Factors
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / etiology
  • Breast Neoplasms / prevention & control*
  • Child
  • Early Detection of Cancer* / adverse effects
  • Early Detection of Cancer* / methods
  • Early Detection of Cancer* / standards
  • Evidence-Based Medicine
  • Female
  • Humans
  • Interdisciplinary Communication
  • International Cooperation
  • Magnetic Resonance Imaging
  • Mammography
  • Mass Screening* / adverse effects
  • Mass Screening* / methods
  • Mass Screening* / standards
  • Neoplasms / radiotherapy*
  • Population Surveillance / methods*
  • Radiotherapy / adverse effects
  • Risk Assessment
  • Survivors*
  • Time Factors
  • Young Adult