Of fish and men: using zebrafish to fight human diseases

Trends Cell Biol. 2013 Dec;23(12):584-6. doi: 10.1016/j.tcb.2013.09.009.


Long restricted to the field of developmental biology, the use of the zebrafish (Danio rerio) has extended to the study of human pathogenesis. Fostered by the rapid adaptation of new technologies, the design and analysis of fish models of human diseases have contributed important findings that are now making their way from aquariums to clinics. Here we outline the clinical relevance of the zebrafish as a model organism.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Disease Models, Animal*
  • Disease*
  • Humans
  • Translational Medical Research
  • Zebrafish / physiology*