The etiology of infectious proctitis in men who have sex with men differs according to HIV status

Sex Transm Dis. 2013 Oct;40(10):768-70. doi: 10.1097/OLQ.0000000000000022.

Abstract

We compared the spectrum of pathogens responsible for infectious proctitis between HIV-positive and HIV-negative men who have sex with men. Only 32% of men with herpes simplex virus (HSV)-associated proctitis had visible external anal ulceration.The etiology of infectious proctitis among HIV-positive and HIV-negative men is as follows: chlamydia (23.4% vs. 21.7%, P = 0.7), gonorrhea (13.4% vs. 10.8%, P = 0.5), HSV-1 (14.2% vs. 6.5%, P = 0.04), HSV-2 (22% vs. 12.3%, P = 0.03), lymphogranuloma venereum (7.8% vs. 0.7%, P = 0.004), and multiple infections (17.7% vs. 8.6%, P = 0.017). Thirty-two percent with HSV proctitis had external anal ulceration.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Australia / epidemiology
  • CD4 Lymphocyte Count
  • Chlamydia Infections / complications
  • Chlamydia Infections / epidemiology
  • Fissure in Ano / epidemiology
  • Fissure in Ano / microbiology
  • Gonorrhea / complications
  • Gonorrhea / epidemiology
  • HIV Seropositivity / complications
  • HIV Seropositivity / epidemiology
  • Herpes Simplex / complications
  • Herpes Simplex / epidemiology
  • Homosexuality, Male* / statistics & numerical data
  • Humans
  • Lymphogranuloma Venereum / complications
  • Lymphogranuloma Venereum / epidemiology
  • Male
  • Mass Screening
  • Proctitis / epidemiology*
  • Proctitis / microbiology*
  • Proctitis / virology
  • Sexual Behavior
  • Viral Load