Transuretral resection of the bladder (TURB): analysis of complications using a modified Clavien system in an Italian real life cohort

Eur J Surg Oncol. 2014 Jan;40(1):90-5. doi: 10.1016/j.ejso.2013.11.003. Epub 2013 Nov 12.

Abstract

Introduction: To evaluate the applicability of a modified Clavien classification system (CCS) in grading postoperative complications of transurethral resection of bladder tumours (TURB).

Materials and methods: A series of patients undergoing monopolar TURB from April 2011 to March 2012 at five Italian centers were enrolled. All complications occurring within the first 30-day postoperative period were prospectively recorded and graded according to the CCS.

Results: Overall, 275 patients were included. Median age was 71 (63/78) years; median BMI was 28 (25.4/30.8) Kg/m(2), median tumour size was 2 (1-3) cm; median number of tumour lesions was 1 (1-3). Median operative time was 30 (20/45) min. Fifty-seven complications were recorded in 43 patients. Overall postoperative morbidity rate was 16%. Most of the complications were not serious and classified as Clavien type I (42 cases; 74%) or II (8 cases, 14%). Higher grade complications were scarce: CCS IIIa in 1 case (2%) and CCS IIIb in six cases (10%). No TURB related death was reported. Six patients were re-operated due to significant bleeding or clot retention on postoperative days 2-7. On univariate (73.5 ± 38 versus 36.7 ± 21.6 min) and multivariate analysis longer operative time was an independent predictor of complications (OR: 1.06 per min, 95%CI 1.04-1.08, p = 0.001).

Conclusions: A modified CCS can be used as a standardized tool to objectively define the complications of TURB which confirms to be a safe procedure with a low surgical morbidity. This tool can be used to aid in patient counselling and to facilitate scientific assessment.

Keywords: Bladder cancer; Clavien; Complications; Transurethral resection.

Publication types

  • Evaluation Study
  • Multicenter Study

MeSH terms

  • Aged
  • Anticoagulants / administration & dosage
  • Carcinoma, Transitional Cell / epidemiology
  • Carcinoma, Transitional Cell / pathology
  • Carcinoma, Transitional Cell / surgery*
  • Cohort Studies
  • Comorbidity
  • Confounding Factors, Epidemiologic
  • Cystectomy / adverse effects*
  • Cystectomy / methods
  • Female
  • Heparin, Low-Molecular-Weight / administration & dosage
  • Humans
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / etiology*
  • Postoperative Complications / prevention & control
  • Postoperative Hemorrhage / diagnosis
  • Postoperative Hemorrhage / etiology
  • Prospective Studies
  • Reoperation
  • Severity of Illness Index
  • Urethra
  • Urinary Bladder Neoplasms / epidemiology
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / surgery*

Substances

  • Anticoagulants
  • Heparin, Low-Molecular-Weight