Association between smoking status and the parameters of vascular structure and function in adults: results from the EVIDENT study

BMC Cardiovasc Disord. 2013 Dec 1:13:109. doi: 10.1186/1471-2261-13-109.

Abstract

Background: The present study analyses the relation between smoking status and the parameters used to assess vascular structure and function.

Methods: This cross-sectional, multi-centre study involved a random sample of 1553 participants from the EVIDENT study.

Measurements: The smoking status, peripheral augmentation index and ankle-brachial index were measured in all participants. In a small subset of the main population (265 participants), the carotid intima-media thickness and pulse wave velocity were also measured.

Results: After controlling for the effect of age, sex and other risk factors, present smokers have higher values of carotid intima-media thickness (p = 0.011). Along the same lines, current smokers have higher values of pulse wave velocity and lower mean values of ankle-brachial index but without statistical significance in both cases.

Conclusions: Among the parameters of vascular structure and function analysed, only the IMT shows association with the smoking status, after adjusting for confounders.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Ankle Brachial Index* / methods
  • Blood Flow Velocity / physiology*
  • Carotid Intima-Media Thickness*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Smoking / epidemiology
  • Smoking / physiopathology*
  • Young Adult