Advances in genomics of bony fish

Brief Funct Genomics. 2014 Mar;13(2):144-56. doi: 10.1093/bfgp/elt046. Epub 2013 Nov 29.


In this review, we present an overview of the recent advances of genomic technologies applied to studies of fish species belonging to the superclass of Osteichthyes (bony fish) with a major emphasis on the infraclass of Teleostei, also called teleosts. This superclass that represents more than 50% of all known vertebrate species has gained considerable attention from genome researchers in the last decade. We discuss many examples that demonstrate that this highly deserved attention is currently leading to new opportunities for answering important biological questions on gene function and evolutionary processes. In addition to giving an overview of the technologies that have been applied for studying various fish species we put the recent advances in genome research on the model species zebrafish and medaka in the context of its impact for studies of all fish of the superclass of Osteichthyes. We thereby want to illustrate how the combined value of research on model species together with a broad angle perspective on all bony fish species will have a huge impact on research in all fields of fundamental science and will speed up applications in many societally important areas such as the development of new medicines, toxicology test systems, environmental sensing systems and sustainable aquaculture strategies.

Keywords: aquaculture; fish models; genomics; medaka; next-generation sequencing; teleosts; zebrafish.

Publication types

  • Review

MeSH terms

  • Animals
  • Fishes / genetics*
  • Genome / genetics
  • Genomics / trends*
  • Models, Animal
  • Sequence Analysis, DNA