Immediate Stroke Life Support (ISLS) is a curriculum for evaluation and management of acute stroke syndromes. ISLS was developed by Japan ISLS task force consisting of Japanese Association of Acute Medicine (JAAM) and Japanese Congress on Neurological Emergencies (JCNE). The course incorporates role play, mannequin simulation modalities, and clinical maps. ISLS has undergone a collaborative iterative process from Japanese to enable English language / North American student participation. ISLS complements the neurological skills and knowledge which are essential to cerebral resuscitation. This program will introduce teachers to the techniques used in this course, through sequential train-the-trainer exercises in each of the integrated simulation techniques.