Dendrimer-like polymeric DNAs as chemiluminescence probes for amplified detection of telomere DNA on a solid-phase membrane

Chem Commun (Camb). 2014 Jan 25;50(7):859-61. doi: 10.1039/c3cc47454b.


For the first time, an amplified chemiluminescence (CL) detection of the telomere DNA spotted on a nylon membrane is described here, based on the direct hybridization with the CL probe of dendrimer-like polymeric DNAs possessing a large number of guanine moieties. This probe was synthesized by sense and antisense hybridization between Y-shaped DNAs and then could hybridize with the target DNA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / analysis*
  • DNA / chemistry
  • Dendrimers
  • Luminescence
  • Membranes, Artificial
  • Nucleic Acid Hybridization
  • Nylons
  • Polymers / chemistry
  • Telomere / genetics


  • Dendrimers
  • Membranes, Artificial
  • Nylons
  • Polymers
  • DNA