Zinc: Role in the management of diarrhea and cholera

World J Clin Cases. 2013 Jul 16;1(4):140-2. doi: 10.12998/wjcc.v1.i4.140.


Diarrhea and cholera are major health problems. Vibrio cholera, the causative agent of cholera, infects the small intestine, resulting in vomiting, massive watery diarrhea and dehydration. Reduced water and electrolyte absorption is also due to zinc deficiency. Zinc has an important role in recovery from the disease. The combination of zinc with cholera vaccine and oral rehydration solutions has a positive impact on cholera and diarrhea. It has led to a decrease in the mortality and morbidity associated with diarrhea.

Keywords: Cholera; Diarrhea; Oral rehydration solutions; Vibrio cholera; Zinc.

Publication types

  • Review