Three-component reaction between alkynes, elemental sulfur, and aliphatic amines: a general, straightforward, and atom economical approach to thioamides

Org Lett. 2014 Jan 3;16(1):310-3. doi: 10.1021/ol403345e. Epub 2013 Dec 5.

Abstract

A general, straightforward, and atom-economical three-component synthesis of thioamides from alkynes, elemental sulfur, and aliphatic amines has been developed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry*
  • Amines / chemistry*
  • Molecular Structure
  • Sulfur / chemistry*
  • Thioamides / chemical synthesis*
  • Thioamides / chemistry

Substances

  • Alkynes
  • Amines
  • Thioamides
  • Sulfur