Pediatric laryngeal neurofibroma: case report and review of the literature

Int J Pediatr Otorhinolaryngol. 2014 Jan;78(1):142-7. doi: 10.1016/j.ijporl.2013.10.047. Epub 2013 Nov 13.

Abstract

Presentation of a case of pediatric laryngeal neurofibroma (LNF) and review of the world literature. Comprehensive review of the world literature using Pubmed and Google scholar. Pediatric LNF was identified in 62 cases reported in the world literature. The most common presenting symptom is stridor and the most common location of the tumor in the larynx is the aryepiglottic fold. Recent reports demonstrate increased utilization of endoscopic resection with reduced need for tracheostomy. Pediatric LNF is a rare disorder. Review of the world literature since 1940 suggests a recent trend away from aggressive open resection and toward more conservative endoscopic resection with excellent functional results.

Keywords: Laryngeal neurofibroma; Neurofibromatosis; Pediatric; Transoral CO(2) laser resection.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Child
  • Humans
  • Laryngeal Neoplasms / diagnosis*
  • Laryngeal Neoplasms / surgery
  • Laryngoscopy / methods*
  • Larynx / pathology*
  • Larynx / surgery
  • Male
  • Neurofibroma / diagnosis*
  • Neurofibroma / surgery