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. 2014 Jan;42(Database issue):D749-55.
doi: 10.1093/nar/gkt1196. Epub 2013 Dec 6.

Ensembl 2014

Paul Flicek  1 , M Ridwan Amode, Daniel Barrell, Kathryn Beal, Konstantinos Billis, Simon Brent, Denise Carvalho-Silva, Peter Clapham, Guy Coates, Stephen Fitzgerald, Laurent Gil, Carlos García Girón, Leo Gordon, Thibaut Hourlier, Sarah Hunt, Nathan Johnson, Thomas Juettemann, Andreas K Kähäri, Stephen Keenan, Eugene Kulesha, Fergal J Martin, Thomas Maurel, William M McLaren, Daniel N Murphy, Rishi Nag, Bert Overduin, Miguel Pignatelli, Bethan Pritchard, Emily Pritchard, Harpreet S Riat, Magali Ruffier, Daniel Sheppard, Kieron Taylor, Anja Thormann, Stephen J Trevanion, Alessandro Vullo, Steven P Wilder, Mark Wilson, Amonida Zadissa, Bronwen L Aken, Ewan Birney, Fiona Cunningham, Jennifer Harrow, Javier Herrero, Tim J P Hubbard, Rhoda Kinsella, Matthieu Muffato, Anne Parker, Giulietta Spudich, Andy Yates, Daniel R Zerbino, Stephen M J Searle
Affiliations

Ensembl 2014

Paul Flicek et al. Nucleic Acids Res. 2014 Jan.

Abstract

Ensembl (http://www.ensembl.org) creates tools and data resources to facilitate genomic analysis in chordate species with an emphasis on human, major vertebrate model organisms and farm animals. Over the past year we have increased the number of species that we support to 77 and expanded our genome browser with a new scrollable overview and improved variation and phenotype views. We also report updates to our core datasets and improvements to our gene homology relationships from the addition of new species. Our REST service has been extended with additional support for comparative genomics and ontology information. Finally, we provide updated information about our methods for data access and resources for user training.

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Figures

Figure 1.
Figure 1.
(A) The scrollable Genoverse view (with view control icons in the upper right corner) provides the overview panel on the Region in Detail page. Image from URL: http://e73.ensembl.org/Homo_sapiens/Location/View?r=6:133017695-133161157. (B) Phenotype data from DDG2P, OMIM, Orphanet, HGMD and COSMIC for the human gene ATP2A2. Image created from URL http://e73.ensembl.org/Homo_sapiens/Gene/Phenotype?db=core;g=ENSG00000174437;r=12:110718561-110788898.
Figure 2.
Figure 2.
Usage and example output for the Ensembl REST server Fetch Variant Consequences endpoint.
See this image and copyright information in PMC

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