Clinical efficacy of a herbal dentifrice on dentinal hypersensitivity: a randomized controlled clinical trial

Aust Dent J. 2013 Dec;58(4):483-90. doi: 10.1111/adj.12109.

Abstract

Background: Dentinal hypersensitivity is a common problem and there is a growing interest in herbal based formulations for the treatment of oral diseases. This study was conducted to assess the efficacy of a commercially available novel herbal dentifrice in reduction of dentinal hypersensitivity.

Methods: A total of 73 subjects (38 males and 35 females; aged 25-60 years) were randomly divided into two groups: Group 1 - a placebo dentifrice (The Himalaya Drug Company Research and Development, Makali, Bangalore) and Group 2 - (test group), a commercially available herbal dentifrice (Hi Ora K, The Himalaya Drug Company Research and Development, Makali, Bangalore). Sensitivity scores for controlled air stimulus and cold water were recorded at baseline, 6 weeks and 12 weeks.

Results: The test group was found to be significantly better compared to the placebo group at the end of 6 and 12 weeks in reduction of dentinal hypersensitivity.

Conclusions: The novel herbal dentifrice can be recommended for treatment of dentinal hypersensitivity.

Keywords: Clinical trial; Spinacia oleracea; dentifrice; dentine desensitizing agents; potassium nitrate.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Air
  • Alkenes / chemistry
  • Cinnamomum zeylanicum / chemistry
  • Dentifrices / therapeutic use*
  • Dentin Sensitivity / drug therapy*
  • Double-Blind Method
  • Female
  • Humans
  • India
  • Male
  • Middle Aged
  • Nitrates / therapeutic use*
  • Phytotherapy / methods*
  • Piperidines / chemistry
  • Plant Extracts / chemistry
  • Potassium Compounds / therapeutic use*
  • Spinacia oleracea / chemistry*
  • Syzygium / chemistry
  • Water
  • Zinc Oxide / therapeutic use

Substances

  • Alkenes
  • Dentifrices
  • Nitrates
  • Piperidines
  • Plant Extracts
  • Potassium Compounds
  • trikatu
  • triphala
  • Water
  • potassium nitrate
  • Zinc Oxide