Genetic profile and cancer-related pain: a tale from two outlier cases with bone metastatic disease

Pain Med. 2014 Apr;15(4):710-2. doi: 10.1111/pme.12314. Epub 2013 Dec 11.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activation, Metabolic / genetics
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / metabolism*
  • Bone Neoplasms / secondary*
  • Catechol O-Methyltransferase / genetics
  • Female
  • Glucuronosyltransferase / genetics
  • Humans
  • Male
  • Middle Aged
  • Morphine / administration & dosage
  • Morphine / metabolism*
  • Neuralgia / drug therapy*
  • Neuralgia / etiology
  • Nociceptive Pain / drug therapy*
  • Nociceptive Pain / etiology
  • Osteosarcoma / secondary*
  • Polymorphism, Single Nucleotide
  • Prostatic Neoplasms / pathology*
  • Receptors, Opioid, mu / genetics
  • Young Adult

Substances

  • Analgesics, Opioid
  • OPRM1 protein, human
  • Receptors, Opioid, mu
  • Morphine
  • COMT protein, human
  • Catechol O-Methyltransferase
  • UGT2B7 protein, human
  • Glucuronosyltransferase