A long-playing CD about the γδ TCR repertoire

Adrian Hayday; Pierre Vantourout

doi:10.1016/j.immuni.2013.11.016

A long-playing CD about the γδ TCR repertoire

Immunity. 2013 Dec 12;39(6):994-6. doi: 10.1016/j.immuni.2013.11.016.

Authors

Adrian Hayday¹, Pierre Vantourout²

Affiliations

¹ Peter Gorer Department of Immunobiology, King's College London, London SE1 9RT, UK; London Research Institute, Cancer Research UK, London WC2A 3LY, UK; Medical Research Council Centre for Transplantation Biology, London SE1 9RT, UK; Comprehensive Biomedical Research Centre of Guy's and St Thomas' Hospitals and King's College London, London SE1 9RT, UK. Electronic address: adrian.hayday@kcl.ac.uk.
² Peter Gorer Department of Immunobiology, King's College London, London SE1 9RT, UK; London Research Institute, Cancer Research UK, London WC2A 3LY, UK.

PMID: 24332025
DOI: 10.1016/j.immuni.2013.11.016

Abstract

In this issue of Immunity, a study by Luoma et al. (2013) provides structural evidence for direct interactions of human Vδ1(+) T cell receptors with CD1d, capping a long trail of evidence that CD1 might be a major influence on γδ T cell biology.

Publication types

Comment

MeSH terms

Animals
Antigens, CD1d / chemistry*
Humans
Lipids / immunology*
Models, Molecular*
Receptors, Antigen, T-Cell, gamma-delta / chemistry*
Receptors, Antigen, T-Cell, gamma-delta / metabolism*
T-Lymphocytes / metabolism*

Substances

Antigens, CD1d
Lipids
Receptors, Antigen, T-Cell, gamma-delta