Perspectives in immunopharmacology: the future of immunosuppression

Immunol Lett. 2014 Oct;161(2):211-5. doi: 10.1016/j.imlet.2013.11.017. Epub 2013 Dec 12.

Abstract

Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in a wide variety of diseases, from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumors, chronic inflammatory and degenerative diseases, metabolic disorders, etc.). This brief review will summarize some of the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression, by considering the following aspects:

Keywords: Immunopharmacology; Immunosuppression; Microbiome; Nanomedicine; Personalized medicine.

Publication types

  • Review

MeSH terms

  • Biological Products / pharmacology
  • Biological Products / therapeutic use
  • Humans
  • Immune System Diseases / drug therapy
  • Immune System Diseases / genetics
  • Immune System Diseases / immunology
  • Immune System Diseases / metabolism
  • Immunity / drug effects*
  • Immunity / physiology*
  • Immunomodulation / drug effects*
  • Immunomodulation / genetics
  • Immunosuppression Therapy
  • Microbiota / immunology
  • Nanomedicine
  • Precision Medicine

Substances

  • Biological Products