Residential radon and lung cancer in never smokers. A systematic review

Cancer Lett. 2014 Apr 1;345(1):21-6. doi: 10.1016/j.canlet.2013.12.010. Epub 2013 Dec 11.


Radon exposure is considered the second cause of lung cancer and the first in never smokers. We aim to assess the effect of residential radon exposure on the risk of lung cancer in never smokers through a systematic review applying predefined inclusion and exclusion criteria. 14 Studies were included. Some of them point to a relationship between residential radon and lung cancer while others show no association. Further studies are necessary to test this association and to assess if other risk factors such as environmental tobacco smoke could modify the effect of residential radon exposure on lung cancer.

Keywords: Lung neoplasms; Never smokers; Radon; Systematic review.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Humans
  • Lung Neoplasms / etiology*
  • Neoplasms, Radiation-Induced / etiology*
  • Radon / poisoning*
  • Risk Factors


  • Radon