Determination of carbonyl compounds generated from the E-cigarette using coupled silica cartridges impregnated with hydroquinone and 2,4-dinitrophenylhydrazine, followed by high-performance liquid chromatography

Anal Sci. 2013;29(12):1219-22. doi: 10.2116/analsci.29.1219.

Abstract

Carbonyl compounds in E-cigarette smoke mist were measured using coupled silica cartridges impregnated with hydroquinone and 2,4-dinitrophenylhydrazine, followed by high-performance liquid chromatography. A total of 363 E-cigarettes (13 brands) were examined. Four of the 13 E-cigarette brands did not generate any carbonyl compounds, while the other nine E-cigarette brands generated various carbonyl compounds. However, the carbonyl concentrations of the E-cigarette products did not show typical distributions, and the mean values were largely different from the median values. It was elucidated that E-cigarettes incidentally generate high concentrations of carbonyl compounds.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / analysis*
  • Aldehydes / chemical synthesis
  • Chromatography, High Pressure Liquid
  • Electrical Equipment and Supplies*
  • Hydroquinones*
  • Phenylhydrazines*
  • Silicon Dioxide*
  • Tobacco Products*
  • Tobacco Use Cessation Devices*

Substances

  • Aldehydes
  • Hydroquinones
  • Phenylhydrazines
  • 2,4-dinitrophenylhydrazine
  • Silicon Dioxide
  • hydroquinone