Safety of elective colorectal cancer surgery: non-surgical complications and colectomies are targets for quality improvement

J Surg Oncol. 2014 May;109(6):567-73. doi: 10.1002/jso.23532. Epub 2013 Dec 11.

Abstract

Background: Mortality following severe complications (failure-to-rescue, FTR) is targeted in surgical quality improvement projects. Rates may differ between colon- and rectal cancer resections.

Methods: Analysis of patients undergoing elective colon and rectal cancer resections registered in the Dutch Surgical Colorectal Audit in 2011-2012. Severe complication- and FTR rates were compared between the groups in univariate and multivariate analysis.

Results: Colon cancer (CC) patients (n = 10,184) were older and had more comorbidity. Rectal cancer (RC) patients (n = 4,906) less often received an anastomosis and had more diverting stomas. Complication rates were higher in RC patients (24.8% vs. 18.3%, P < 0.001). However, FTR rates were higher in CC patients (18.6% vs. 9.4%, P < 0.001). Particularly, FTR associated with anastomotic leakage, postoperative bleeding, and infections was higher in CC patients. Adjusted for casemix, CC patients had a twofold risk of FTR compared to RC patients (OR 1.89, 95% CI 1.06-3.37).

Conclusions: Severe complication rates were lower in CC patients than in RC patients; however, the risk of dying following a severe complication was twice as high in CC patients, regardless of differences in characteristics between the groups. Efforts should be made to improve recognition and management of postoperative (non-)surgical complications, especially in colon cancer surgery.

Keywords: colon cancer; failure to rescue; postoperative complications; postoperative mortality; rectal cancer.

Publication types

  • Comparative Study

MeSH terms

  • Age Distribution
  • Aged
  • Clinical Audit
  • Colectomy / methods
  • Colectomy / statistics & numerical data*
  • Colonic Neoplasms / surgery*
  • Comorbidity
  • Elective Surgical Procedures
  • Female
  • Humans
  • Intensive Care Units
  • Laparoscopy / statistics & numerical data
  • Length of Stay / statistics & numerical data
  • Male
  • Multivariate Analysis
  • Postoperative Complications / epidemiology*
  • Quality Improvement
  • Quality of Health Care
  • Rectal Neoplasms / surgery*
  • Retrospective Studies
  • Surgical Stomas / statistics & numerical data