Cannabis Finds Its Way Into Treatment of Crohn's Disease

Pharmacology. 2014;93(1-2):1-3. doi: 10.1159/000356512. Epub 2013 Dec 17.

Abstract

In ancient medicine, cannabis has been widely used to cure disturbances and inflammation of the bowel. A recent clinical study now shows that the medicinal plant Cannabis sativa has lived up to expectations and proved to be highly efficient in cases of inflammatory bowel diseases. In a prospective placebo-controlled study, it has been shown what has been largely anticipated from anecdotal reports, i.e. that cannabis produces significant clinical benefits in patients with Crohn's disease. The mechanisms involved are not yet clear but most likely include peripheral actions on cannabinoid receptors 1 and 2, and may also include central actions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / therapeutic use*
  • Cannabinoids / therapeutic use*
  • Cannabis*
  • Crohn Disease / drug therapy*
  • Humans

Substances

  • Anti-Inflammatory Agents
  • Cannabinoids