Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 68 (1), 50-6

Systematic Review of the Effects of Exercise on Activities of Daily Living in People With Alzheimer's Disease

Affiliations
Review

Systematic Review of the Effects of Exercise on Activities of Daily Living in People With Alzheimer's Disease

Ashwini K Rao et al. Am J Occup Ther.

Abstract

OBJECTIVE. Alzheimer's disease (AD) results in a loss of independence in activities of daily living (ADLs), which in turn affects the quality of life of affected people and places a burden on caretakers. Limited research has examined the influence of physical training (aerobic, balance, and strength training) on ADL performance of people with AD. METHOD. Six randomized controlled trials (total of 446 participants) fit the inclusion criteria. For each study, we calculated effect sizes for primary and secondary outcomes. RESULTS. Average effect size (95% confidence interval) for exercise on the primary outcome (ADL performance) was 0.80 (p < .001). Exercise had a moderate impact on the secondary outcome of physical function (effect size = 0.53, p = .004). CONCLUSION. Occupational therapy intervention that includes aerobic and strengthening exercises may help improve independence in ADLs and improve physical performance in people with AD. Additional research is needed to identify specific components of intervention and optimal dosage to develop clinical guidelines.

Figures

Figure 1.
Figure 1.
Forest plot of effect sizes for the comparison of exercise versus control groups on the primary outcome of activity of daily living performance. Note. CI = confidence interval; SD = standard deviation.
Figure 2.
Figure 2.
Forest plot of effect sizes for the comparison of exercise versus control groups on the secondary outcome of physical function. Note. CI = confidence interval; SD = standard deviation.
Figure 3.
Figure 3.
Forest plot of effect sizes for the comparison of exercise versus control groups on the secondary outcome of cognition and mood. Note. CI = confidence interval; SD = standard deviation.

Similar articles

See all similar articles

Cited by 21 articles

See all "Cited by" articles
Feedback