Changes in the organization of the genome during the mammalian cell cycle

Genome Biol. 2013 Dec 24;14(12):142. doi: 10.1186/gb4147.


By using chromosome conformation capture technology, a recent study has revealed two alternative three-dimensional folding states of the human genome during the cell cycle.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Cycle*
  • Chromatin / genetics
  • Chromosomes, Human / genetics*
  • Chromosomes, Mammalian / genetics
  • Genome, Human*
  • Humans
  • Imaging, Three-Dimensional / methods*
  • Nucleic Acid Conformation


  • Chromatin